The Germany international defender, who joined the club from Valencia in the summer, is set for a prolonged period on the sidelines after sustaining a hamstring problem.
Shkodran Mustafi
Shkodran Mustafi has been ruled out for the remainder of the year with a hamstring injury, Arsene Wenger has confirmed.
The Germany defender was substituted during Arsenal's 3-1 victory over Stoke City on Saturday.
And Wenger has revealed that Mustafi was withdrawn from the encounter due to a serious injury that will rule the German out until after Christmas.
“He has a bad hamstring strain and will be out for a minimum of 21 days. He will have a good Christmas [not playing]," Wenger told reporters after the game.
Mustafi has enjoyed a smooth transition into English football following his summer move to the club from Valencia, playing 17 games for Arsenal and collecting a mere three yellow cards.
Arsenal are currently top of the Premier League on goals scored after their defeat of the Potters, but Chelsea could overtake them if they beat West Brom on Sunday.